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Alan H. Jobe
USA
Alan H. Jobe
Emeritus Professor
Department of Paediatrics
University of California
- Professor of Paediatrics at Cincinnati Children’s Hospital
- Contributed towards the research of surfactant metabolism, hormonal regulation of lung maturation, mechanisms of lung injury with mechanical ventilation, and neonatal resuscitation.
- 30 years collaborative research project on fetal development and antenatal steroids.
Antenatal Steroids-Too Much, Too Little, or Just Nice?
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Alistair Gunn
New Zealand
Alistair Gunn
Professor of Physiology & Paediatrics
Starship Children’s Hospital
Head, Department of Physiology
Faculty of Medicine & Health Sciences
University of Auckland
- Professor of Physiology & Paediatrics
- conducted ground-breaking basic research into ways of identifying compromised fetuses in labour, monitoring the evolution of brain injury and the mechanisms and treatment of asphyxial brain injury.
- His research helped to establish mild cooling as the first ever technique to reduce brain injury due to low oxygen levels at birth.
Brain Function Monitoring in Asphyxiated Infants
Perinatal hypoxia-ischemia (HI) is still a significant contributor to mortality and adverse neurodevelopmental outcomes in term and preterm infants. HI brain injury evolves over hours to days, and involves complex interactions between the endogenous protective and pathological processes. Understanding the timing during the evolution of injury is vital for guiding treatments. Post-HI recovery is associated with a typical neurophysiological profile, with stereotypic changes in EEG activity, cerebral perfusion and oxygenation. After the initial recovery, there is a delayed, prolonged reduction in cerebral perfusion mediated by endogenous metabolic suppression, followed by secondary deterioration with seizures, hyperperfusion and increased cerebral oxygenation, associated with altered neurovascular coupling and impaired cerebral autoregulation. These changes in cerebral perfusion are associated with the stages of evolution and injury severity. In this presentation, we will review evidence that changes in EEG, cerebral oxygenation and metabolism after HI may be useful biomarkers of prognosis.
Therapeutic Drifts in Hypoxic Ischaemic Encephalopathy
Therapeutic hypothermia (TH) is now well established to improve intact survival after neonatal encephalopathy (NE). However, since the completion of the randomized controlled trials there has been substantial therapeutic drift because many specific situation could not included in the trials. Should we cool late preterm newborns with NE? Is cooling beneficial for mild NE? Is cooling for 72 hours optimal, or should we cool for longer? Will either milder or deeper hypothermia be effective? Why was TH not effective in the HELIX trial? In this presentation I will dissect the underlying pathophysiological principles that can guide practice and future research.
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Alvin SM Chang
Singapore
Alvin SM Chang
Clinical Director Quality, Safety and Risk Management (QSRM) Senior Consultant Department of Neonatology
KK Women's and Children's Hospital
- Clinical Director for quality, safety and risk management
- Senior consultant neonatologist in KK Women’s and Children’s Hospital, Singapore.
- Chairs the Patient Safety and Risk Council
- Associate editor of Frontiers in Paediatrics and Journal of Patient Safety and Quality in Healthcare.
Culture Eats Strategy–Building Robust Systems
While leadership plays an important role in setting strategic priorities of the organization, organizational culture plays an extremely important role at executing these priorities at ensuring a reliable safety and quality of care. Organizational culture is a shared way of thinking, feeling and behaving within the institution itself. It can be the culprit leading to downfalls of healthcare organizations. On the other hand, the right organizational culture can be a remedy for learning organizations to improve their safety and quality of care. The recently published Ockenden report highlighted failings in the perinatal services of the Shrewsbury and Telford Hospitals NHS Trust. There was poor antenatal care for vulnerable women, repeated failures to correctly assess fetal growth, reluctance to refer women to tertiary centres to address fetal abnormalities, poor management of multiple pregnancies, poor management of gestational hypertension, failure to recognize sick or deteriorating women, failure to act on abnormal fetal heart patterns and failure to escalate concerns. These were the result of shortcomings within the leadership and teamwork. There was a culture of bullying and concerns raised by staff were taken lightly. This stemmed from poor working relationships, poor risk assessment, grossly inadequate response to adverse incidents, lack of board grip, inadequate clinical governance and emphasis on ‘normal’ birth particularly in high risk pregnancies at the expense of good care. The patients’ voices were ignored leading to a gross lack of empathy in handling poor outcomes, mortalities and bereavement support. As leaders, senior clinicians in the system need to be cognizant of team dynamics and communication among their members. Creating a psychologically safe environment for people to raise concerns and to learn from it for improvement is essential. This should include partnering and hearing the voices of patients. Leadership sets the culture. In turn, the culture determines the direction the organization is heading. A culture that promotes learning would steer away from merely blaming individuals for errors. In a psychologically safe environment, mistakes and errors are viewed as learning opportunities to strengthen the system. Focusing on this will help create robust processes to ensure a highly reliable delivery of care.
Large Scale Initiatives to Reduce Harm
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Anup Katheria
USA
Anup Katheria
Associate Professor & Director
Neonatal Research Institute
Sharp Mary Birch Hospital for Women & Newborns, San Diego
- Director of Neonatal Research Institute in Sharp Mary Birch Hospital for Women & Newborns.
- The Medical Director of High-risk infant follow-up clinic and Course Director for Neonatal Ultrasound Program in Neonatal research Institute.
- An avid researcher with interest in delayed cord clamping in preterm infants, and the effects of surfactant and caffeine on newborn haemodynamics.
Neonatal Resuscitation: What’s New?
Surfactant Delivery – Minimal, Less, and Least Invasive
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Atul Malhotra
Australia
Atul Malhotra
Associate Professor (Research) & NHMRC Fellow
Consultant Neonatologist & Head
Early Developmental Clinic
Monash Children’s Hospital & Monash University, Melbourne
- A senior consultant neonatologist in Monash Children’s Hospital.
- The current recipient of NHMRC Emerging Leadership Fellowship and has published over 100 journal articles.
- Led the world first clinical trial of placental stem cells for treatment of chronic lung disease in premature neonates.
Targeting the Inflamed Lung & Sepsis-Use of Human Amnion Epithelial Cells
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Ben Willem Mol
Australia
Ben Willem Mol
Professor & Consultant Obstetrician & Gynaecologist
Department of Obstetrics & Gynaecology
Monash University
- A Professor of Obstetrics & Gynaecology in Monash University.
- His research focuses mainly on routine everyday practices that led to many landmark studies.
- Holds continuous NHMRC funding since 2014.
- Acknowledged as one of the most prolific medical scientists.
Controversies in Management of Cervical Insufficiency
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Boris W. Kramer
Netherlands
Boris W. Kramer
Professor of Pediatrics
School for Mental Health and Neuroscienc
Maastricht University
- A Professor of Paediatrics in School of Mental Health and Neuroscience, Maastricht University, Netherlands.
- Professor for Experimental Perinatalogy.
- Director of Paediatric Research.
- Main interest: development of lung, gut brain and immune system after preterm birth.
Stem Cells! Stem Cells?
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Brian Carter
USA
Brian Carter
Professor & Consultant Neonatologist
Chairman
Department of Medical Humanities & Bioethics
University of Missouri-Kansas School of Medicine
- Professor of Paediatrics in University of Missouri-Kansas City School of Medicine.
- Chairman of Medical Humanities & Bioethics Department
- Editor-in-Chief of Clinical Paediatrics
- Main interest: treatment outcome, neonatal aftercare, bioethics and prenatal diagnosis
Tinier and Tinier-Moving Targets for Definition of Viability
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Byung Min Choi
South Korea
Byung Min Choi
Professor & Consultant Neonatologist
Department of Paediatrics
College of Medicine, Korea University, Seoul
- A Professor of Paediatrics in Korea University College of Medicine.
- President of the Korean Society of Perinatology.
- Main interest is in neonatal haemodynamics and neonatal cardiology.
- Recent publication: Association of delayed initiation of non-invasive respiratory support with pulmonary air leakage in outborn late preterm and term neonates.
Massive Pulmonary Haemorrhage
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Carmencita Padilla
Philippines
Carmencita Padilla
Professor & Director of Paediatrics
School of Medicin
University of the Philippines, Manilla
- Professor of Paediatrics at the College of Medicine, University of the Philippines
- Chancellor of University of the Philippines Manila
- Founding Director of Institute of Human Genetics
- Has more than 170 publications
Screening for Inborn Errors of Metabolism - A Cost-Effective Method
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Cecilia Villalain
Spain
Cecilia Villalain
Fetal Medicine Unit – Maternal & Child Health & Development Network
Hospital Universitario 12 de Octubre Madrid
- A Maternal and fetal Medicine consultant in Octubre University Hospital in Madrid.
- Completed her PhD in fetal growth restriction.
- During the Covid-19 pandemic, she was one of the main researchers on Covid-19 in pregnancy in her centre.
- Main interest: placental dysfunction, fetal congenital anomalies
Recommendations from World Association of Perinatal Medicine (WAPM)-Clinical management of COVID-19 in pregnancy
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Chang Yun Sil
South Korea
Chang Yun Sil
Professor of Paediatrics
Department of Paediatrics
Sungkyunkwan University School of Medicine
- Professor of Paediatrics in Sungkyunkwan University School of Medicine, Korea
- Director of Stem Cell & Regenerative Medicine Institute and Korean Neonatal Network
- Main interest:improving survival of extreme preterm infants and the translational bench to bedside stem cell research to treat bronchopulmonary dysplasia.
Stem Cells for BPD
Bronchopulmonary dysplasia (BPD) is a chronic lung disease associated with ventilator and oxygen therapy in very premature infants. Although the number of very preterm infants at high risk of developing BPD has increased due to recent advances in neonatal intensive care, BPD remains a significant cause of death and lifetime morbidities without effective ways to prevent or treat it. Thus, a new treatment modality is urgently needed to improve the prognosis of this intractable disorder. Previous preclinical studies have shown that mesenchymal stem cells (MSCs) attenuate hyperoxic-induced neonatal lung injury in an animal model simulating BPD of human infants. In a first in human phase 1 clinical trial, we have demonstrated that intratracheal transplantation of umbilical cord blood derived MSCs for bronchopulmonary dysplasia (BPD) is safe and feasible in very preterm infants. Then, we performed a randomized, double-blind, placebo-controlled phase II clinical trial to investigate the therapeutic efficacy of MSCs (1× 107 cells/kg) for BPD. It was conducted on 66 preterm infants born at 23 to 28 weeks of gestation and received mechanical ventilator support with respiratory deterioration between 5 and 14 postnatal days. The primary outcome of death or moderate to severe BPD was not significantly different between the control and MSC group. However, subgroup analysis revealed that MSC transplantation decreased secondary outcome of severe BPD in subgroup infants of 23 to 24 weeks, not in 25-28 weeks of gestation. We recently completed 5-year long-term follow-up study for these enrolled patients and the results are pending. Accordingly, we are now conducting an additional larger randomized double-blinded placebo-controlled phase II clinical trial that focuses on extremely preterm infants of 23 to 24 weeks of gestation. (NCT03392467).
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Daigo Ochiai
Japan
Daigo Ochiai
Associate Professor
Department of Obstetrics & Gynaecology
Keio University, Tokyo
- Consultant in Obstetrics & Gynaecology Department at Keio University School of Medicine.
- Specializes in perinatology, fetal cardiology and obstetrics ultrasound.
- One of the top leader in the field of regenerative medicine particularly in amniotic fluid stem cells research
Amniotic fluid derived mesenchymal stem cell-Perinatal Treatment
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David Ellwood
Australia
David Ellwood
Professor of Obstetrics & Gynaecology and Director of the Maternal-Foetal Medicine Unit,
Gold Coast University Hospital
Dean of Medicine, and Head School of Medicine and Dentistry at Griffith Universit
Gold Coast University Hospital and Griffith University
- Professor of Obstetrics & Gynaecology and the past President of FAOPS
- Dean of Medicine at Griffith University, Queensland.
- Director of Maternal Fetal Medicine in Gold Coast University Hospital.
- Main interest:preventing adverse pregnancy outcomes
Preventing Prematurity & Stillbirths
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Eiji Hirakawa
Japan
Eiji Hirakawa
Professor in Neonatology
Chief
Department of Neonatology
Kagoshima City Hospital, Kagoshima
- Neonatology Consultant and Chief of Neonatology Department in Kagoshima City Hospital in Japan.
- Received grants for Neonatal aero transport research
- Published papers on Safety, speed and effectiveness of air transportation for neonates and Impact of the obstetrician and neonatologist staffed doctor helicopter in Japan.
Neonatal Transport & Retrieval in Japan
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Elena Cavazzoni
Australia
Elena Cavazzoni
Consultant Paediatric Intensivist & Palliative Care Medicine Specialist
Co-State Medical Director for the NSW Organ and Tissue Donation Service
Children's Hospital, Westmead
- Consultant in Paediatrics Intensive Care Unit in Westmead Children’s Hospital
- Clinical lecturer in Sydney University
- Medical Director for New South Wales Organ and Tissue Donation Service
- Main interest:organ and tissue donation, transfusion medicine and neurocritical care
The Littlest Angels–Establishment of Neonatal Organ & Tissue Donation Services
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Foong Yen Lim
USA
Foong Yen Lim
Professor of Surgery
Surgical Director of Fetal Care Centre
Cincinnati Children's Hospital Medical Centre, Cincinnati, Ohio
- Professor in Paediatrics Surgery
- Surgical Director of Fetal Care Center at Cincinnati Children’s Hospital Medical Center
- Perform fetoscopy, minimally invasive procedures and open surgeries
- Helps to build one of the world top fetal surgery program Also develop educational animation videos
Ensuring Survival of Babies with Severe Congenital Diaphragmatic Hernia
EXIT Procedures-Latest Advances
Severe Congenital Diaphragmatic Hernia: Changing the Outcomes
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Han Suk Kim
South Korea
Han Suk Kim
Professor of Paediatrics
Department of Paediatrics
Seoul National University Children’s Hospital
Seoul National University College of Medicine
- Consultant Neonatologist and Professor in Paediatrics at Seoul National University College of Medicine
- Director of SNU Children’s Hospital
- Main interest:basic and clinical research on neonatal lung disease
- Had published papers on infection control in NICU and clinical etiology of neonatal diseases
Clinical Practice of Neurally Adjusted Ventilatory Assist (NAVA) in the NICU
Neurally adjusted ventilatory assist (NAVA) is a new ventilatory mode that allows the patient to synchronize spontaneous respiratory effort via the detection of an electrical signal from the diaphragm muscle. By utilizing the electrical activity of the diaphragm (EAdi), NAVA can synchronize mechanical ventilatory breaths with the patient’s neural respiratory drive and proportionally support this drive. Theoretically, by maintaining spontaneous breathing and improving the patient-ventilator interaction, NAVA may be able to prevent premature lung damage by avoiding high- pressure or high volume support and providing more physiologic mechanical ventilatory support. Neurally adjusted ventilator assist (NAVA) was introduced to our unit via crossover-RCTs to assess its safety and physiological effects. First, mechanically ventilated preterm infants were randomized to crossover ventilation with NAVA and SIMV-PS for 4-hour each to determine the physiologic effects of NAVA (J Pediatr 2012). Peak inspiratory pressure (PIP), work of breathing, and peak-EAdi with NAVA were lower. Calculated TV to peak-EAdi ratio and PIP to peak-EAdi ratio were higher with NAVA. Second, we conducted another crossover-RCT to compare non-invasive NAVA (NI-NAVA) and NI-PS on patient-ventilator synchrony( ADC-F&E 2015). Maximum-Edi, swing-Edi and PIP were lower during NI-NAVA. All types of asynchronies and Asynchrony-index were reduced with NI-NAVA. In our unit, intubated-NAVA has been mainly applied for infants with higher and/or prolonged ventilatory support. Our cohort studies showed NAVA 1) improved ventilator variables and blood gas values in infants with BPD (PCCM. 2016) and 2) reduced cyanotic episodes and sedatives and dexamethasone uses for infants on prolonged mechanical ventilation (Pediatr Int. 2017). We have used NI-NAVA as a weaning mode from intubated ventilation. Our pilot-study suggested that NI-NAVA might have advantages in reducing extubation-failure compared to nCPAP (BMC Pediatr. 2019) and we has conducted an RCT to determine the clinical advantage of NIV-NAVA compared to nCPAP after extubation in preterm infants (NCT02590757).
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Hugh Simon Lam Hung San
Hong Kong S.A.R
Hugh Simon Lam Hung San
Professor
Department of Paediatrics
Chinese University of Hong Kong
- Professor of Paediatrics
- Assistant Dean (Academics) in Medical Faculty of Chinese University of Hong Kong
- 2nd Vice President of the Hong Kong Neonatal Society
- President of Hong Kong College of Paediatricians
- Main interest:sleep/wake patterns in young children and environmental impact on child health
Can’t Intubate, Can’t Ventilate –What Next?
Intubation is a core skill that allows a neonatal resuscitation provider to control the airway and more effectively oxygenate and ventilate a newborn infant in cardiopulmonary failure. When intubation and ventilation are indicated, but is technically difficult, the time delay can result in rapid deterioration. It is important for resuscitators to have alternative techniques to control a newborn infant’s airway at their disposal. In this lecture these techniques will be discussed.
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James Michael Roberts
USA
James Michael Roberts
Professor of Obstetrics & Gynaecology
Magee Women’s Research Institute, University of Pittsburgh
- Co-investigator of Global Pregnancy Collaboration
- Chairman of NICHD and ACOG Taskforce to establish guidelines for hypertension in pregnancy
- Main research:fundamental, clinical and health services approaches to the understanding and management of preeclampsia
Global CoLab Collaborative
One of the greatest opportunities for accelerating research progress is the enormous power of current computer technology to agnostically analyze huge amounts of data. This allows an understanding of physiology and pathophysiology as never before. This is particularly relevant to pregnancy where not only must we understand the complexity of the interactions of genes and environments but must do this for two individuals – mother and baby. This opportunity comes with challenges. How does one share data never meant to be shared? How can we economically collect biological materials? How do we determine the important research questions? How do we prevent this level of complexity from increasing the disparities between high income and low income settings? These considerations led to the formation of the Global Pregnancy Collaboration (CoLab). Begun with funding by the Bill and Melinda Gates Foundation in 2010, CoLab is a consortium of over 40 centers from high and low resource settings around the world. The original goal of CoLab was sharing of data and biological samples. This was successful, resulting in several publications. However, three facts quickly became evident. 1. The best recognized sources of data and biosamples excluded low resource countries that were vastly underrepresented. 2. There is more to collaboration than sharing.3. There is more to sharing than merging (attempting to merge) disparate data and differently collected biosamples. Based upon this CoLab extended its mission to increase the involvement of low resource settings in collaborative efforts. This included improving research infrastructure both human and analytical. We also moved to facilitate merging of data and biosamples through designing and encouraging harmonized data sets and participating in the standardization of biological sample collection. Working with investigators from high and low resource settings we sponsored workshops to identify questions in pregnancy research that required increased attention. The results were then published with recommendations in high impact journals. We also provide virtual educational presentations aimed at beginning investigators in low resource settings. In my presentation I will provide examples of what CoLab is doing and plans to do and how this can be useful to members of the audience.
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Jason Gardosi
United Kingdom
Jason Gardosi
Consultant Obstetrician & Gynaecologist
Professor of Maternal and Perinatal Health
Director of the Perinatal Institute Birmingham
University of Warwick
- Honorary Professor of Maternal & Perinatal Health at University Warwick
- Founder and executive director of Perinatal Institute, Birmingham UK
- Receives awards for Princess Royal Training Award and Queen’s award for the international program to improve fetal growth surveillance
- Main interest:reducing stillbirths, improvement of fetal growth surveillance
Progress in Stillbirth Prevention: International Perspectives
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John Lantos
USA
John Lantos
Professor Dr
Professor of Paediatrics & Director of Bioethics
School of Medicine, University of Missouri–Kansas City School of Medicine, Director of the Children's Mercy Bioethics Center at Children's Mercy Hospital.Children's Mercy Hospital
- Professor of Paediatrics and Bioethicist
- Founding Director of Children’s Mercy Hospital Bioethics Center
- Had written hundreds of papers on pediatric bioethics
- Latest book: Kidney To Share, The Ethics of Shared Making Decision
Lethal No More-Saving Babies with Multiple Anomalies
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Ju Lee Oei
Australia
Ju Lee Oei
Professor Dr
Consultant Neonatologist
Royal Hospital for Women, Randwick, Sydney
- Consultant Neonatologist, Royal Hospital for Women, Sydney, Australia
- Conjoint Professor at University of New South Wales
- Chair of Perinatal Substance Use Special Interest Group of PSANZ
- Main interest: use of oxygen in newborn resuscitation, perinatal substance use disorders, neonatal epidemiology
Lasting Generations: Substance Abuse in Mothers
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Jun Takeda
Japan
Jun Takeda
Associate Professor
Department of Obstetrics & Gynaecology
Juntendo University, Faculty of Medicine, Tokyo
- Associate Professor of O&G Department in Juntendo University, Tokyo, Japan
- A member of several guidelines' committees
Treatment of Post-Partum Bleeding in Japan
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Koert de Waal
Australia
Koert de Waal
Associate Professor
Consultant Neonatologis
John Hunter Children's Hospital, Newcastle, NSW
- Consultant Neonatologist in John Hunter Children’s Hospital, Newcastle, Australia
- Completed his PhD in central blood flow measurements
- Main interest:neonatal haemodynamics and cardiac ultrasound
- Trained in Royal Prince Alfred Hospital, Sydney to master functional echocardiography
Neonatal Hypovolaemic Shock: Surviving the plunge
True hypovolemic shock is rare in neonates and is mostly seen early after birth. Causes include peripartum bleeding from the fetal side of the placenta, feto-maternal haemorrhage, feto-fetal hemorrhage or a postpartum hemorrhage of the neonate. With ongoing bleeding, the autonomic sympathetic system is activated with inhibition of the parasympathetic system leading to increased heart rate, cardiac contractility and arterial and venous tone. Blood volume from the non-vital organs and the venous system will be recruited to help preserve blood flow to the brain, heart and adrenal glands. If the bleeding cannot be stopped, severe hypovolemia will finally lead to severe acidosis and myocardial dysfunction, organ failure and death. The optimal approach to hemorrhagic hypovolemia in neonates has not been well studied. Most of what is known about physiology and management has been extrapolated from animal and adult data. Rapid replacement of the type of the fluid lost, most frequently whole blood, is the key approach along with appropriate supportive measures. Noradrenaline is the first line of vasopressor-inotrope used in adults as it induces significant venoconstriction at the level of the splanchnic circulation in particular. Echocardiography can be effectively used to monitor systemic perfusion during hypovolemic shock in neonates and to test fluid responsiveness at the bedside.
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Laila Arjumand Banu
Bangladesh
Laila Arjumand Banu
Chief Consultant of Obstetrics & Gynaecology
Lab Aid Specialised Hospital, Dhaka
- Chief Consultant and Head of department of Obstetrics & Gynaecology in Lab Aid Specialised Hospital, Dhaka
- President of Bangladesh Perinatal Society
- Deputy Secretary of FAOPS
- Secretary General of Gynaecological Endoscopy Society of Bangladesh
- Treasurer of Fertility & Sterility Society of Bangladesh
- Treasurer of Bangladesh Menopause Society
Risk Assessment of Unbooked Mothers in Labour
Definition-Unbooked mothers are those who have no antenatal care who delivered within 3 days of initial booking visit. Booked mothers are those who had regular antenatal check up according to WHO criteria or regional criteria (2-8 visits). There are many studies or researches-the results are more or less same-in only one study done in Harare (Zimbabwe)-they showed that fetomaternal complications are more in booked patients because those patients are already with some obstetric comlications-so the pregnancy outcome is more worse than unbooked patients. But in most of the studies-It has shown that in case of unbooked patients-the obstetric condition is unknown to labor staffs- and they ended up with emergency caesarean section, laparotomy due to rupture uterus,worse perinatal outcome and neonatal complications. To achieve the SDG-30-most of the countries implement various programs and projects to improve the maternal and neonatal health and to reduce the maternal and neonatal mortality rates.These programs are mainly Government programs in collaboration with NGO, development partners, professional bodies etc. In many countries- organized antenatal care provided by different organization are exist-but specially in developing countries the number of unbooked mothers vary from 2% to 38%.They are a great burden for the labor room of the tertiary centers . Usually the unbooked mothers are young, healthy, needs more emergency casarean section, operative delivery , sometimes laparotomy for rupture uterus increasing the maternal and neonatal mortality and morbidity. So to reduce the maternal and neonatal mortality-number of unbooked patient should be decreased by awareness, providing quality and organized antenatal check up proper referral, sometimes by giving some incentives for antenatal care.
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Lakshminrusimha Satyanarayana
USA
Lakshminrusimha Satyanarayana
Professor
Consultant Neonatologist,
Nancy and Dennis Marks Chair of Pediatrics and the Pediatrician-in-Chief
UC Davis Children's Hospital, Sacramento
- Professor of Paediatrics and Consultant Neonatologist.
- Paediatrician-in-Chief with UC Davis Children’s Hospital.
- Nancy and Dennis Marks Chair of Paediatrics.
- Member of American Academy of Paediatrics Neonatal Resuscitation Steering Committee.
- Main interest in clinical and translational research evaluating scientific basis of neonatal resuscitation, role of oxygen during transition at birth and in newborns.
Babies with Hypoxaemic Respiratory Failure
Hypoxemic respiratory failure (HRF) is often associated with persistent pulmonary hypertension of the newborn (PPHN). This combination (HRF + PPHN) is seen in both preterm and term infants. The approximately incidence is around 2 per 1000 live births in the US. Neonates present with respiratory distress, labile hypoxemia and in some cases, differential cyanosis (lower oxygen saturations -SpO2 – in the lower limbs compared to right upper limb). Most cases of HRF/PPHN are secondary to lung disease such as meconium aspiration syndrome (MAS), congenital diaphragmatic hernia (CDH), respiratory distress syndrome (RDS), pneumonia, transient tachypnea of the newborn (TTN) and asphyxia. However, some cases are not associated with lung disease and are due to pulmonary vascular remodeling or hyperactivity and are known as idiopathic or “black-lung” PPHN.
The diagnosis of HRF/PPHN is established by echocardiography. Absence of anatomical cardiac defect, right-to-left or bidirectional shunt at the level of the patent foramen ovale (PFO) or patent ductus arteriosus (PDA), right ventricular hypertrophy or dysfunction, bulging of the interventricular septum to the left and tricuspid regurgitation are common echocardiographic features of HRF/PPHN. The management is based on diagnosis. In parenchymal lung disease such as MAS, pneumonia and RDS, optimal lung recruitment with respiratory support to provide adequate mean airway pressure (including mechanical ventilation if needed), surfactant, along with supplemental oxygen is needed. In patients with hypoplastic lungs such as CDH, gentle ventilation with low pressures will minimize volutrauma to the fragile lungs. If these measures are not adequate, pulmonary vasodilator therapy with inhaled nitric oxide (iNO), IV/PO sildenafil and IV milrinone may be considered. Approximately 20-30% of patients with HRF/PPHN may not respond to mechanical ventilation and pulmonary vasodilator therapy. The most common reason for poor response in inadequate lung recruitment. Using adequate PEEP or mean airway pressure to open the lungs to functional residual capacity is crucial to reduce pulmonary vascular resistance (PVR) and optimize delivery of iNO. Managing hemodynamics with appropriate fluid and vasopressor support is needed in 30-40% of patients with HRF/PPHN. If all these measures fail, extracorporeal membrane oxygenation (ECMO) may be warranted.
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Lata Srinivasan
India
Lata Srinivasan
Head of Department
Perinatal Pathology
Mediscan System
- Perinatal Pathologist for 25 years
- Had done 15000 fetal/perinatal autopsies
- Special interest:congenital heart disease and skeletal anomalies
- Had dissected many small hearts (12-14 weeks gestation)
The Fetal Autopsy–Why, When & How
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Lesley Kuliukas
Australia
Lesley Kuliukas
Course Coordinator of Master of Midwifery
Curtin University
- A midwife of over 30 years
- Course Coordinator of Bachelor of Science Midwifery in Curtin University, Perth, Australia
- Has experience as a hospital and homebirth midwife
- Main interest: Simulation in Midwifery
Teaching Midwifery–From Obstetric Simulation to Real World Practice
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Liona Poon Chiu Yee
Hong Kong S.A.R
Liona Poon Chiu Yee
Professor
Department of Obstetrics & Gynaecology
Chinese University of Hong Kong
- Professor of Obstetrics & Gynaecology in Chinese University of Hong Kong
- Academic subspecialist in MFM
- Has published more than 200 papers
- Main interest: early prediction and prevention of preeclampsia
Reducing Maternal Mortality Across Asia -Challenges & Efforts
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Manuel Sanchez Luna
Spain
Manuel Sanchez Luna
Associate Professor
Director of Neonatology Division
Hospital General Universitario Madrid
- Medical Director of NICU.
- Professor of Paediatrics at University Hospital Gregorio Maranon, Madrid, Spain.
- President of Spanish National Society of Neonatology.
- Main interest in BPD, respiratory physiology and septic shock and personalized nutrition.
HFOV with Volume Guarantee–The Evidence
The knowledge that the ventilator induced lung injury (VILI) in premature Newborn infants with respiratory failure can trigger Bronchopulmonary Dysplasia (BPD) modified recently the respiratory support applied to these population to a gentler and a less invasive mechanical ventilation, and the combination of initial lung stabilization with early surfactant therapy decrease the most severe forms of BPD. But in some cases, it is still needed to intubate and use invasive mechanical ventilation. In this situation, the use of High Frequency Ventilation (HFV) has been proposed as an alternative to conventional ventilation from 1970s, as this technique can be beneficial due to its efficacy to recruit a collapsed lung and washout more CO2 with less lung trauma. Although HFV can reduce the incidence of VILI and BPD, due to the use of different protocols, devices and clinical situations, the medical evidence of the potential benefits of the elective use over CMV is low. More recently, the use of a well-defined lung recruitment protocols with a high lung-volume strategy and the possibility of measuring and controlling in a very precise manner the high frequency tidal volumes (VThf) during HFV with new ventilators offers a new alternative. Also, measurement of the VThf can be an important advantage for a better control of HFV, as there is a narrow correlation of the VThf and the CO2 washout. So as today it is possible to decrease VThf during HFV by fixing it with the VG, CO2 washout can be maintained constant by increasing the frequency. This effect in the lung was recently demonstrated in a neonatal animal model of RDS where the use of an approach of very low VThf at high frequencies produced a lung protective effect by a lower histologic damage score. This new strategy has been demonstrated to be feasible in newborn infants with respiratory failure, even extremely immature infants. In our experience and using this new strategy, of an earlier use of HFOV+VG combined with the use of higher frequencies and lower tidal volume is associated to an increase in survival without bronchopulmonary dysplasia in immature infants.
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Marta Cohen
United Kingdom
Marta Cohen
Professor
Consultant Paediatric and Perinatal Pathologist
Sheffield Children’s Hospital
- Consultant Paediatrician and Perinatal Pathologist in University of Sheffield.
- Board member of International Society for Study and Prevention of Perinatal and Infant Death.
- Council member of European Society of Pathology.
- Main interest in perinatal, and sudden infant death investigations, placenta and paediatric GIT pathology.
Medicolegal concerns for investigation after death
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Melinda Cruz
Australia
Melinda Cruz
Honorary Research Associate
National Health and Medical Research Council
CEO, Founder and a Board Director of Miracle Babies Foundation
- Co-founder of Miracle Babies Foundation in Australia
- Has personal experience delivering 3 premature babies requiring NICU care
- A trusted parent expert to medical professionals
- An investigator on several neonatal trials including Family Integrated Care Trial
- A trusted parent expert to medical professionals
Providing parental support for parents of babies in NICU
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Milind Rajkumar Shah
India
Milind Rajkumar Shah
Consultant Obstetrician
Professor & Head of Department
Department of Obstetrics & Gynaecology
Gandhi Natha H. Medical College Naval Nursing Home, South Kasba Solapur
- President of Indian Society of Perinatology
- Honorary treasurer for FAOPS.
- Professor and Head of Obstetrics & Gynaecology Department, Gandhi Natha H.Medical College.
- Contributed more than 20 chapters in various books.
Triaging in the Management of Pre-Eclampsia
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Mohammad Shahidullah
Bangladesh
Mohammad Shahidullah
Professor
Head of Neonatology Department
Bangabandhu Sheikh Mujib Medical Centre
- Professor and Head of Neonatology Department, Bangabandhu Sheikh Mujib Medical Centre, Bangladesh
- Secretary General, Childhealth Foundation
- Contributor of almost all teaching and training manuals on Essential Newborn Care in Bangladesh
Impact of COVID-19 on Perinatal Health in FAOPS Region
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Nitin Gangadhar Chaubal
India
Nitin Gangadhar Chaubal
Professor Emeritus
Consultant Radiologist
Director
Thane Ultrasound Centre, Mumbai
- Professor Emeritus at D.Y Patil University Navi Mumbai.
- Consultant Radiologist in Jaslok Hospital & Research Centre, Mumbai, India.
- Director of Thane Ultrasound Centre.
- Published more than 40 articles.
Dopplers & Monitoring Methods for Fetal Growth Restriction -When to Intervene
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Pang Nguk Lan
Singapore
Pang Nguk Lan
RN, Paediatric Intensive Care Unit
Director Department of Quality, Safety and Risk Management
KK Women's and Children's Hospital
- A RN with more than 20 years of PICU experience.
- Director, Quality Safety and Risk Management.
- Chief Risk Officer in KK Women’s and Children’s Hospital, Singapore.
- Consultant, National Improvement Unit with Ministry of Health.
- Initiated the Safety and Reliability-Zero Harm Program in 2014.
Leadership Role in Attaining Zero Harm
Most health care organizations are striving to attain high reliability with zero harm as the aim to mitigate adverse events while consistently providing high-quality care in the context of a rapidly changing environment. The governance framework and program structure are fundamental elements that required to drive and lead their people towards a shared value to achieve the zero harm. However, as the safety field evolves, there is a growing recognition of the role that organizational leadership plays in prioritizing safety and embrace the belief that all injuries are preventable and that no injury is acceptable. Management's safety leadership lays the foundation upon which a solid system is built and leaders are the key influencers on the safety culture of an organization. The vital success to establishment of safety is through actions which create a strong culture in responding to patient and staff concerns with strong engagement and supporting efforts to improve safety by encouraging staff to speak up, reporting unsafe conditions and system, help people make the best choices and monitoring progress. Apart from having leaders to demonstrate safety through its actions, commitment, measures, and recognitions, the attitude, behaviour, and style of management can have a powerful effect on workforce safety to improve patient outcomes as well as to improve safety for healthcare workers.
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Patricia Woods
Australia
Patricia Woods
Consultant Neonatologist
Centre for Neonatal Research and Education
King Edward Memorial Hospital
- Consultant Neonatologist in King Edward Memorial Hospital, Australia
- Has certification of Clinician Performed Ultrasound for Neonatologists with ASUM council
- A faculty lecturer with ASUM workshops
- Main interest: use of point-of-care Lung ultrasound in neonatology
Pitfalls in Functional Lung Ultrasound
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Ranjan Kumar Pejavar
India
Ranjan Kumar Pejavar
Professor of Neonatology & Chief Neonatologist
People Tree Hospital @ Meenakshi Hospital Bangalore
- Professor and Chief of Neonatology in People Tree Meenakshi Hospital, Bangalore, India.
- Editor in chief for Perinatology Journal.
- Past President of FAOPS.
- Founder of IAP Immunize India project, world’s largest immunization program.
Innovations in Saving Babies-From the Past to The New World
India: Getting Together-Emergence of the Delta Wave
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Rima S.Bader
Saudi Arabia
Rima S.Bader
Professor of Paediatrics and Perinatal Cardiology
King Abdul Aziz University
- Professor of Paediatrics and Perinatal Cardiology in King Abdul Aziz University, Saudi Arabia
- Founder and President of Fetal Gulf Heart Group
- Editorial board member of the Saudi Heart Journal
- Published The Perinatal Cardiology Handbook
Pitfalls with Fetal Cardiac Scans-Universal vs Target Groups
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Satoshi Kusuda
Japan
Satoshi Kusuda
Professor
Consultant Neonatologist
Tokyo Health Care University, Neonatal Research Network of Japan, Kyorin University, Tokyo
- Clinical Professor at Tokyo Health Care University and Kyorin University, Japan.
- Director of Neonatal Research Network of Japan.
- Current President for FAOPS.
- Main research interest includes network databases and neonatal respiratory care.
Tiny yet Mighty-Care of Extremely Preterm Infants
Although the mortality rate among extremely preterm infants has been improving over time, morbidities among them are not reduced to an acceptable level yet. There is also a variation in the limit of viability, use of antenatal corticosteroid, choice of delivery mode, initiation of resuscitation, NICU care, and follow-up of survivors among extremely preterm infants. These variations can be attributable to the lack of a standardized approach in care based on strong evidence proved by well-designed clinical trials. Therapeutic drifts exist there. There are several reasons why clinical trials were not sufficiently performed until recently. The major reason was due to high mortality rate. If the majority of infants enrolled in clinical trials died, it would be very difficult to prove the benefit of new treatment due to high background noise. Therefore, most practices in NICU for extremely preterm infants have been developed by clinical experiences rather than randomized clinical trials. Accumulated realistic experiences from the front line of NICU care have provided in a way strong support for clinicians. In fact, as mentioned above, the current mortality rate among extremely preterm infants has been declining and reached about 10% by virtue of available clinical knowledge. In this sense, we should appreciate of thoughtfulness and tremendous efforts of many predecessors in modern neonatal medicine. However, in order to achieve further improvement in outcomes of extremely preterm infants, basic and translational research which could fill the current knowledge gaps and new drug/device development in neonatal medicine are mandatory. Since 1980 when Prof. Fujiwara introduced pulmonary surfactant therapy for infants with respiratory distress syndrome, only limited interventions were studied and developed for the care of extremely preterm infants. Now when the mortality rate among extremely preterm infants decreased enough, it is the most suitable time for introducing innovative care into our NICU through evidence-based medicine. For this purpose, international collaboration is essential because clinical trials involving tiny infants are not easy, even for countries with advanced neonatal care.
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Seno Adjie
Indonesia
Seno Adjie
Consultant Obstetrician & Gynaecologist,
Department of Obstetrics & Gynaecology
Rumah Sakit St Carolus, Jakarta
- Consultant Obstetrician & Gynaecologist in Rumah Sakit St Carolus, Indonesia.
- Secretary General of Indonesia Perinatology Association.
- Chief in Advance Labour and Risk Management Course.
- National trainer for Neonatal Resuscitation Program and Adolescent Reproductive Health Training.
Indonesia: Saving Lives- Management Dilemmas with Limited Resources
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Setyadewi Lusyati
Indonesia
Setyadewi Lusyati
Consultant Neonatologist
Department of Paediatrics
National Women and Child Health - Harapan Kita Hospital
- Consultant Neonatologist in National Women and Child Health, Harapan Kita Hospital, Indonesia
Rescuing Neonates in Low- & Middle-Income Countries
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Sheila M Gephart
USA
Sheila M Gephart
Associate Professor
College of Nursing
The University of Arizona, Tucson
- Associate Professor, College of Nursing, University of Arizona, USA.
- A nurse for 20 years and also a nurse scientist since 2012.
- Member of NEC Society Scientific Advisory Council
- Member of Editorial Board of Advances in Neonatal Care.
- Main interest: timely recognition and prevention for NEC.
Towards Zero NEC–Risk Awareness Tools
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Sheng-Wen Shaw
Taiwan
Sheng-Wen Shaw
Assistant Prof. Dr.
Department of Obstetrics & Gynaecology
Taipei Chang Gung Memorial Hospital
- Assistant Professor in Obstetrics & Gynaecology Department, Taipei Chang Gung Memorial Hospital, Taiwan.
- Honorary Senior Research Associate with Fetal Medicine Unit, University College London Hospital.
- Research interest: in utero gene and stem cell therapy, prenatal cytogenetic and molecular diagnosis.
Expanding the Scope of Non-Invasive Prenatal Testing (NIPT)
The Littlest Angels–Establishment of Neonatal Organ & Tissue Donation Services
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Socorro De Leon-Mendoza
Philippines
Socorro De Leon-Mendoza
President
Kangaroo Mother Care Foundation, Philippines, Inc.
President of Kangaroo Mother Care Foundation, Philippines. Emeritus Fellow of the Philippine Paediatric Society. Immediate past President of FAOPS. Has contributed to research and policy formulation in the Philippines.
Philippines: Business as Usual?–Breastfeeding & Skin-to-Skin
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Suresh Seshadri
India
Suresh Seshadri
Chief Medical Director
Consultant Foetal Sonologist
Mediscan Systems
- Consultant Maternal and Fetal Medicine.
- Director of Mediscan Systems, Chennai, India.
- Honorary Secretary of Voluntary Health Services.
- Visiting Professor in Perinatology, Chennai & PSG Hospital.
- Trained in fetoscopy and laser surgery in Necker Hospital, Paris.
- Main interest in prenatal diagnosis and fetal therapy.
Fetoscopic Laser Ablation for Monochorionic Twins
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Sylvia Lim Gibson
Australia
Sylvia Lim Gibson
Perinatal Psychiatrist
Royal Hospital for Women, NSW
- Perinatal Psychiatrist with Royal Hospital for Women, NSW, Australia.
- Chief Director of Naamuru Parent Baby Unit at Royal Prince Alfred Hospital.
- Clinical Director of Perinatal Infant Mental Health Service Sydney Local Health District.
Post-Partum Depression
There is increasing recognition of perinatal anxiety and depression as a significant and common complication of childbirth and as a distinct phenomenon beyond the commoner and usually self-resolving postnatal blues. Untreated perinatal depression persists and has wide ranging and longlasting adverse sequelae of the affected women, their partners as well as the emotional, cognitive and developmental outcomes of their children. It also leads, in severe cases, to suicide and infanticide. Estimates of costs of untreated perinatal depression are significant ranging from lost productivity, maternal health expenditure, child behavioural and health outcomes and child injury. Despite this, the condition is often under-recognised and under-treated. The early identification, diagnosis and effective treatment of perinatal depression vitally needs to be included in holistic maternal infant health care. This paper reviews the current understanding of perinatal anxiety and depression, common presentations, risk and predisposing factors and treatment options. It also explores the role of cultural and societal factors in the prevalence and course of perinatal anxiety and depression, including the role of traditional birthing and parenting practices, migration and societal role changes. Most cases of perinatal depression, if identified early, respond to treatment in the primary care setting without escalation to specialist psychiatric care and this presentation examines the role of maternity and paediatric services, general practitioners and primary health care in the treatment. Antenatal identification of risk and predisposing factors and possible early identification and prevention strategies explored.
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Takushi Hanita
Japan
Takushi Hanita
Vice Director of Centre for Perinatal Medicine, Tohoku University Hospital
Associate Professor & Consultant Paediatrician
Department of Paediatrics
Tohoku University School of Medicine Sendai,
- Associate Professor & Consultant Paediatrician with Tohoku University, Japan
Tiniest Babies’ Amazing Race - The Artificial Placenta
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Tan Hak Koon
Singapore
Tan Hak Koon
Professor of Obstetrics & Gynaecology
Chairman & Senior Consultant
Department of Obstetrics & Gynaecology
KK Women's and Children's Hospital
- Chairman and Professor of Obstetrics & Gynaecology in KK Women’s and Children’s Hospital, Singapore.
- Immediate past President of the College of Obstetricians & Gynaecologist Singapore.
- He specializes in high risk pregnancy and ultrasound scans.
Our People–Resilience in Academic Medicine
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Tetsuya Isayama
Japan
Tetsuya Isayama
Consultant Neonatologist
Head of Division of Neonatology for National Centre for Child Health & Developmen
National Center for Child Health and Development
- Head of Neonatology Division in Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development (NCCHD), Tokyo, Japan.
- Director of Asian Neonatal Network Collaboration.
- Main interest in neonatal and perinatal epidemiology, international comparison studies on clinical practice and outcomes, systematic reviews and clinical practice guidelines.
Asian Neonatal Collaborative Network
The reduction of neonatal death is one of the focuses of the Sustainable Development Goals (SDGs) adopted in the United Nations Sustainable Development Summit in 2015. Although the neonatal mortality has been improving, it still remains high in low- and middle-income countries (LMICs). Therefore, how to reduce the neonatal mortality in LMICs is a key issue in global health. The top cause of neonatal death was prematurity followed by asphyxia. Therefore, the improvement in the care of preterm infants as well as birth asphyxia is important to reduce global neonatal death. Many countries or regions developed national neonatal networks, which are the groups of people and facilities who collaborates to improve the quality of care and outcomes of newborn infants in neonatal intensive care units. In Japan, the Neonatal Research Network Japan (NRNJ) was established in 2004. The NRNJ currently includes approximately 190 NICUs across Japan and maintains national neonatal database of very preterm infants. Furthermore, the NRNJ has been collaborating with other national or regional neonatal networks in high-income countries in a project called iNEO. Wide variations in clinical practice and outcomes of preterm infants were found between the countries or regions in the iNEO. The information has been used for benchmarking and quality improvement to improve preterm infants’ outcomes in each country or region in the iNEO. Following the success of the iNEO, we recently launched another new international collaboration in Asia; Asian Neonatal Network Collaboration (AsianNeo). The AsianNeo includes eight countries (Indonesia, Japan, Malaysia, Philippines, Singapore, South Korea, Taiwan, and Thailand). The aims of the AsianNeo are (1) to understand the differences in systems, clinical management and outcomes of sick newborn infants, (2) to improve the quality of neonatal care in participating countries or regions by applying the obtained knowledge and adopting methods of quality improvement, (3) to accelerate the communication among Asian neonatal networks, and (4) to educate young pediatricians and neonatologists. The uniqueness of the AsianNeo is the inclusion of both high-income countries and LMICs in Asia to learn from each other. In this presentation, I will introduce the current activities of the AsianNeo and the future perspectives of these collaborations.
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Tim Draycott
United Kingdom
Tim Draycott
Vice President RCOG, Professor & Consultant Obstetrician
Department of Obstetrics & Gynaecology
North Bristol NHS Trust
- Professor and Consultant Obstetrician in Southmead Hospital
- Vice President of RCOG
- He led the development of PROMPT (Practical Obstetric Multiprofessional Training)
- Main interest: patient safety, quality improvement, multi-professional obstetric training
Assisted Vaginal Birth for the 21st Century
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Tuangsit Wataganara
Thailand
Tuangsit Wataganara
Associate Professor
Maternal Fetal Medicine Consultant
Mahidol University
- Chief Division of Maternal Fetal Medicine in Faculty of Medicine Siriraj Hospital, Bangkok, Thailand
- President of Medical Ultrasonic Society of Thailand
- Main interest:prenatal screening, diagnosis & therapy, preeclampsia
- Had published more than 100 articles
In-Utero Myelomeningocoele Repair
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Victor Samuel Rajadurai
Singapore
Victor Samuel Rajadurai
Professor & Consultant Neonatologist
Department of Neonatology
KK Women and Children's Hospital
- Senior Consultant in Neonatology Department, KK Women’s and Children’s Hospital, Singapore.
- Vice President of Perinatal Society of Singapore.
- President elect of FAOPS.
- Founding Director of National Expanded Newborn Screening Program.
- Main interest in perinatal asphyxia, PPHN, chronic lung disease of prematurity and hypoglycaemia.
Preventing Brain Damage from Hypoglycaemia
Neonatal hypoglycaemia is the most common biochemical abnormality occurring in 15-20% newborn infants. About 10% require more intensive treatment and sub-optimal management may cause irreversible neurological sequelae. Persistent and recurrent hypoglycaemia can severely impair brain growth and its function. The duration of hypoglycaemia has a larger effect on brain injury rather than the severity of hypoglycaemia. The blood glucose threshold for neonatal hypoglycaemic brain injury (NHBI) is controversial and remains unclear. The pathological changes of NHBI characteristically involve gray matter of posterior parieto-occipital regions of brain bilaterally. The cerebellum and brainstem are often not involved and haemorrhagic lesions are rare. Hypoglycaemia and cerebral hypoxia synergistically accentuate neuronal injury. MRI and MRS are the more sensitive and specific screening methods for diagnosing NHBI and they are superior to ultrasound and CT. Skin-to-skin care soon after birth and early initiation of breast feeding have shown to improve glucose homeostasis and are the most important factor for the prevention of NHBI. The management of the neonate needs to be based on a feed-centric pathway. The use of buccal glucose gel has markedly reduced the need for parenteral glucose administration and separation of the mother-infant dyad. It is more effective than milk feeds alone in reversing asymptomatic hypoglycaemia in infants ≥35 weeks gestation. The possibility of hyperinsulinemia as the underlying cause in persistent or recurrent hypoglycaemia must be considered particularly in infants after 72 hours of life. The etiologic factors include intra-uterine growth restriction (IUGR), infants of diabetic mothers (IDM) and Beckwith-Wiedemann syndrome, islet cell dysregulation syndrome and metabolic disorders. In these cases, the plasma glucose levels need to be kept above 3.5 mmol/l to prevent brain injury. They may need treatment with Diazoxide, Glucagon and/or Octreotide in addition to parenteral glucose. Genetic studies and DOPA pet scan in refractory cases enable to distinguish between focal & diffuse lesions in the pancreas and optimise therapy. Wide fluctuations of blood glucose and hyperglycaemia may aggravate brain injury, hence avoided. Early intervention programme can promote the functional reorganization of the central nervous system, promote the recovery and regeneration of injured brain cells in these high-risk infants.
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Willem de Boode
Netherlands
Willem de Boode
Consultant Neonatologist
Radboudumc Amalia Children's Hospital, Nijmegen
- Consultant Neonatologist in Radboudumc Amalia Children’s Hospital, Netherlands.
- Member of European Society for Paediatric Research.
- Main interest, neonatal haemodynamics, extracorporeal life support and acid base balance.
Managing PPHN with Continuous Haemodynamic Monitoring
Cardiac Output Monitoring in Newborn Infants
LOCAL FACULTY
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Azanna Ahmad Kamar
Azanna Ahmad Kamar
Associate Professor
Consultant Neonatologist, Department of Paediatrics
University Malaya Medical Centre
- A senior consultant and Head of neonatology unit in UM Medical Centre.
- Past President of Perinatal Society of Malaysia.
- Main interest in paediatric bioethics, ventilation, infant nutrition, infection control and neonatal innovations.
- Completed certificate in Paediatric Bioethics from Children’s Mercy Hospital.
Justice in Providing Maternal Somatic Support
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Bavanandam Naidu
Bavanandam Naidu
Maternal Foetal Medicine Consultant
Department of Obstetrics & Gynaecology
Hospital Sultanah Bahiyah
- A senior MFM consultant in Hospital Sultanah Bahiyah.
- A member of Maternal Fetal Subspecialty Committee, Ministry of Health.
- MFM Sub Committee chairperson in OGSM 2014-2018.
- President of Perinatal Society of Malaysia 2013-2014.
The Distressed Fetus! Timeliness of Intervention
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Gan Gin Gin
Gan Gin Gin
Professor & Consultant Haematologist
Department of Medicine
University Malaya
- A Professor and Consultant Haematologist in Universiti Malaya.
- President of Malaysian Society of Haematology.
- Committee member of clinical haematology training in Malaysia.
- Main interest: genetic polymorphism, haematopoietic stem cell transplantation, lymphoma and myeloma.
Low Platelets, at Due Date! The Options
Managing thrombocytopenia in pregnancy can be challenging. About 5-10% of pregnant women have documented thrombocytopenia, which is usually defined as platelet counts of < 150x109/L. Most common cause of thrombocytopenia during the third trimester is gestational thrombocytopenia, which usually do not require any treatment and will resolve spontaneously after delivery. Other causes include pre-eclampsia, HELLP syndrome and hematological disorders such as immune thrombocytopenia purpura (ITP) and thrombotic thrombocytopenia purpura (TTP), which is rare but can be life-threatening. In this talk, I will be focusing on ITP and TTP. For ITP, the goal is to reduce the risk of bleeding for both mothers and babies, while minimizing adverse effects from therapy. Treatment options usually depend on the platelet counts. The first line of treatment is usually corticosteroids, with prednisolone being the preferred choice. Intravenous immunoglobulin is also commonly used in patients who are steroid refractory or resistant. Increasingly, there are other therapeutic options such as rituximab, the new TPO agonist such as eltrombopag , which have shown to not cause major adverse effect in pregnancies. Acquired TTP is not common and can occur during 1st pregnancy and postpartum. This is likely due to the fall in ADAMTS13 level and rise of von Willebrand factor. It is crucial to have high index of suspicion especially when patients present with hemolytic anemia and thrombocytopenia. Relevant investigations such as measurement of ADAMTS 13 levels are important to differentiate from other causes. Treatment of choice for TTP is to commence plasmapheresis as soon as possible.
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Hamizah Ismail
Hamizah Ismail
Associate Professor
Consultant Obsterician & Gynaecologist, Head of Department
International Islamic University Malaysia
- Senior Consultant Obstetrician & Gynaecologist and Maternal & Fetal Medicine Specialist in International Islamic University Malaysia.
- Vice Chairman for Maternal Fetal Medicine Society.
- Main interest:fetal growth, placenta accreta spectrum, maternal nutrition and human milk bank
Role of Maternal Nutrition -The DOHaD Hypothesis
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Hasdy Haron
Hasdy Haron
Manager
National Transplant Resource Centre
Kementerian Kesihatan Malaysia
- Manager of National Transplant Resource Centre in the Ministry of Health.
Malaysia Perspectives
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J Ravichandran
J Ravichandran
Senior Consultant Maternal Fetal Medicine
Department of Obstetrics & Gynaecolog
Hospital Sultan Aminah, Johor Bahru
- Senior Consultant of Maternal and Fetal Medicine
- Former Head of O&G Services in Malaysia
Malaysia: At the Peak of COVID Crisis in Pregnant Women–Can it be Worse?
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Muniswaran Ganesan
Muniswaran Ganesan
Maternal Foetal Medicine Consultant
Head of MFM Unit
Department of Obstetrics & Gynaecolog
Hospital Tunku Azizah, Kuala Lumpur
- Head of MFM unit and Consultant in Women and Children’s Hospital, Kuala Lumpur.
- Completed his training in MFM in UK.
- President of Malaysia Obstetrics Medicine Society.
- His passion is to establish obstetric medicine services in Malaysia and improve the quality of care for women with medical disorders.
Simulation Training in Perinatal Emergencies: The ICOE Experience
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Murali Ganesalingam
Murali Ganesalingam
Consultant Obstetrics & Gynaecology
Senior Lecturer
International Medical University
- Consultant Obstetrician & Gynaecologist in Ampang Hospital
- Has Postgraduate Diploma in Medical Law
- The current Head of Obstetrics & Gynaecology Services for Selangor
- Main interest:gynaecology oncology and high risk pregnancies
Medicolegal Perspectives of Birth Injuries
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Nur Aishah Mohd Taib
Nur Aishah Mohd Taib
Professor & Consultant Breast & Endocrine Surgeon
Department of Surger
University Malaya
- Senior Consultant Breast Surgeon in UMMC
- Professor of Surgical Department.
- Head of UM Cancer Research Institute.
- Member of National Committee for breast and endocrine surgery specialist evaluation.
- Main areas of interest is strongly correlated with patient care and outcomes.
Breast Cancer-Dilemmas of Each Trimester
Gestational breast cancer occurs during pregnancy, the first post-partum year, or lactational period. Patients often present with more advanced diseases, as breast cancer is unexpected in the childbearing years and difficulty detecting lumps in pregnant breasts. The management of breast cancer is dependent on the stage of the disease and the gestation of the pregnancy. In the first trimester, surgery can be performed, and chemotherapy can be instituted within 6 to 12 weeks later during the second trimester. Thus, termination of pregnancy(TOP) is rarely required. They are non-therapeutic and do not affect the prognosis of the patient incurable breast cancer. However, TOP can be considered if the prognosis is poor or if there are other social issues on her ability to care for her child. The dilemma occurs in stage 4 cancers, as in every trimester, the primary objective is always to save the mother. In the first trimester, options for TOP must be discussed if there could be a delay in instituting life-saving systemic therapy in high volume life-threatening metastatic disease. Especially when the patient is not fit for systemic treatment, best supportive care to palliate and support the patient as long as possible to reach pulmonary maturity of the fetus. Staging the disease during pregnancy is usually done with a chest x-ray with abdominal shielding and an ultrasound to assess for liver metastases. Non-contrasted MRI of the spine may be used to evaluate for bone metastases. The diagnosis of cancer is fraught with not just physical impacts but psychosocial ones, the patient, must contend with not just the threat of losing her life but her unborn child. Therefore, it would be mandatory for teams managing these patients to provide psychosocial support and not withstanding to assign patients to social workers or counselors to help them and their family to make medical decisions that need to be made in a timely manner. Either breast conserving or mastectomy can be reasonable options for patients depending on suitability and preference of the patients. As mentioned, systemic therapy can be used in the second and third trimesters. The systemic therapy used are chemotherapy, targeted Her2 therapies like trastuzumab and hormonal treatments are contraindicated. The delivery is an electively planned event, the last systemic therapy must be stopped 3 to 4 weeks before delivery to reduce complications related to neutropenia and thrombocytopenia. In utero exposure to systemic therapy has been documented in small case series, showing low complication rates, with IUGR being the most common. Gestational breast cancer patients are often delivered more preterm. Long term outcomes of babies in utero during cancer treatments show that there is no increase in malignancy or long-term problems when compared to non-breast cancer gestational age-matched controls. Gestational breast cancer compared to non-breast cancer pregnant individuals are associated with a higher risk of death, a large meta-analysis found this is limited those diagnosed in the post-delivery period. In another study, this was found to be both diagnosed during pregnancy or the post-partum period. The talk will further discuss the dilemmas in the three trimesters.
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See Kwee Ching
See Kwee Ching
Consultant Paediatrician & Neonatologist,
Department of Paediatrics
Hospital Sungai Buloh
- Consultant Neonatologist and Head of NICU in Sg Buloh Hospital, Malaysia
- Member of Royal College of Paediatrics and Child Health, Malaysian Paediatric Association, Perinatal Society of Australia and New Zealand
- Involved in care of neonates during Covid-19 pandemic
Resuscitation of Newborns at Risk of COVID-19
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Sheila Gopal Krishnan
Sheila Gopal Krishnan
Consultant Paediatrician
Department of Paediatrics
Hospital Seri Manjung, Perak
- Head of Paediatric Department at Hospital Seri Manjung, Perak.
- Co-chair the ethics committee at the same centre.
- Completed a certificate course in paediatric bioethics at Mercy Hospital, USA.
- Main interest in children’s rights, child protection and clinical ethics.
Moral Distress in Health Care Workers
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Tan Geok Chin
Tan Geok Chin
Professor
Deputy Dean of Research & Innovation, Faculty of Medicine & Professor of Paediatric/Perinatal Patholog
National University of Malaysia
- Consultant Paediatric and Perinatal Pathologist in UKMMC.
- Deputy Dean of Research & Innovation of Medical Faculty, UKM.
- Completed Paediatric Pathology Fellowship training in Nationwide Children’s Hospital, USA.
- Main interest, Paediatric and Perinatal Pathology.
Examination of the Placenta– Training the Trainees
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TP Baskaran
TP Baskaran
Maternal Fetal Medicine Consultant
Gleneagles Hospital, Kuala Lumpur
- Consultant Maternal & Fetal Medicine in Gleneagles Hospital, Kuala Lumpur.
- Medical Director of Fetal Scan Centre, Kuala Lumpur.
- President Elect for Perinatal Society Malaysia.
- Main interest and expertise, fetal medicine.
Dilemmas of Perimortem Caesarean Sections
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Vallikannu Narayanan
Vallikannu Narayanan
Associate Professor
Maternal Fetal Medicine Consultant
Universiti Malaya
- Consultant of Maternal Fetal Medicine, Obstetrics & Gynaecology Department, UMMC
- A graduate of Masters in O&G from UMMC in 2005
- Obtained fellowship in O&G ultrasound from Mediscan Centre
Preventing Shoulder Dystocia
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Wan Ahmad Hafiz bin Wan Md Adnan
Wan Ahmad Hafiz bin Wan Md Adnan
Associate Professor & Consultant Nephrologist
Department of Medicine (Nephrology)
University Malaya
- Nephrology Consultant in Medical Department, UMMC.
- Had worked in Ireland for a few years.
- Received research scholarship from Massachusetts General Hospital, Boston.
- Actively involved in the management of women with kidney disease in pregnancy.
Renal Failure in Pregnancy
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Wu Loo Ling
Wu Loo Ling
Consultant Paediatric Endocrinologist
Subang Jaya Medical Centre, Selangor
- Consultant Paediatric Endocrinologist in Subang Jaya Medical Centre.
- Former lecturer in UKM for more than 30 years.
- One of the core trainers and examiner for paediatric endocrine subspecialty training in Malaysia.
- Main interest, diabetes, growth disorders, sex development in children.
Hypothyroidism in Preterm & Ill Babies
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Zaleha Abdullah Mahdy
Zaleha Abdullah Mahdy
Professor and Maternal Fetal Medicine Consultant
Department of Obstetrics and Gynaecolog
National University of Malaysia
- Professor and Senior Consultant of Maternal Fetal Medicine
- Past President of Perinatal Society Malaysia
- Has published in various journals and books
- Main interest: customized antenatal growth chart, medical virtual reality and drone transportation service for emergency medical care
Losing to Save-Termination of Pregnancy
Monitoring with Perinatal Telehealth
Pre Congress and Hands on workshops
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Afidah Yusoff
Malaysia
Afidah Yusoff
Obstetrician & Gynaecologist Maternal Fetal Medicine Fellow
Hospital Tunku Azizah Kuala Lumpur
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Anand a/l Sanmugan
Malaysia
Anand a/l Sanmugan
Consultant Paediatric Surgeon Paediatric Surgical Unit Department of Surgery University of Malaya
UMMC
- Consultant Paediatric Surgeon in UMMC.
- UMMP OSCE Coordinator for Surgical Department.
- Member of Covid-19 task force.
- Masters of Paediatric Surgery Selection and Intake Coordinator.
- Had published in numerous national and international journals.
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Annellee Camet
Singapore
Annellee Camet
A senior manager, Quality, safety and Risk Management
KK Women’s and Children’s Hospital
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Bernard Wong Yih Terng
Singapore
Bernard Wong Yih Terng
Deputy Group Director SingHealth DUKE-NUS Institute for Patient Safety & Quality (IPSQ) Chief Risk Officer & Director Quality, Safety and Risk Management (QSRM)
KK Women’s & Children’s Hospital
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Buvanes Chelliah
Malaysia
Buvanes Chelliah
Consultant Obstetrician & Gynaecologist Maternal Fetal Medicine Specialist
Hospital Tunku Azizah Kuala Lumpur
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Cheong Shu Meng
Malaysia
Cheong Shu Meng
Consultant Paediatrician & Neonatologist,
Sunway Medical Centre, Kuala Lumpur
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Elizabeth Evans
Australia
Elizabeth Evans
Clinical Nurse Consultant Pain Management Service
Sydney Children’s Hospital, Randwick
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Emily Butler
United Kingdom
Emily Butler
Midwifery Program Manager, Perinatal Institute, UK
The University of Wolverhampton West Midlands, United Kingdom.
The University of Wolverhampton West Midlands
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Eric Ang Boon Kuang
Malaysia
Eric Ang Boon Kuang
Consultant Neonatologist Department of Paediatrics
Hospital Sultanah Bahiyah Kedah
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Haymalatha a/p Rajagam
Malaysia
Haymalatha a/p Rajagam
Nursing Tutor and Neonatal Nurse
Institut Latihan Kementerian Kesihatan Malaysia Sultan Azlan Shah, Tanjung Rambutan, Perak
- Nursing tutor in Institut Latihan Kementerian Kesihatan Malaysia, Sultan Azlan Shah.
- PhD holder in Science (IT management).
- Certified Advanced Practitioner Neocognitive Behavioural Therapist.
- Certified Mental Health First Aider by Malaysia Mental Health Association.
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Jeyanthi Kulasegarah
Malaysia
Jeyanthi Kulasegarah
Assoc. Professor, Consultant Paediatric Otorhinolaryngologist & Head of Department Department of Otorhinolaryngology Faculty of Medicine
University of Malaya Kuala Lumpur
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Jeyasakthy Saniasaya
Malaysia
Jeyasakthy Saniasaya
Paediatric Otorhinolaryngology Specialist
Department of Otorhinolaryngology Faculty of Medicine
University of Malaya Kuala Lumpur
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Juyoung Lee
South Korea
Juyoung Lee
Associate Professor Department of Paediatrics
Inha University College of Medicine
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Khairul Anuar Zainun
Malaysia
Khairul Anuar Zainun
Forensic Pathologist & Head of Department Forensic Medicine Department
Hospital Serdang
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Matthew Chong Hon Loon
Malaysia
Matthew Chong Hon Loon
Consultant Paediatrician & Neonatologist
Gleaneagles Kota Kinabalu Sabah
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Neha Sethi
Malaysia
Neha Sethi
Consultant Obstetrician & Gynaecologist Department of Obstetrician & Gynaecologist
Universiti Malaya Medical Centre, Kuala Lumpur
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Nur Syahrina Rahim
Malaysia
Nur Syahrina Rahim
Associate Professor & Consultant Pathologist Faculty of Medicine & Health Science
USIM
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Nurdaliza Mohd Badarudin
Malaysia
Nurdaliza Mohd Badarudin
Consultant Paediatric Surgeon & Head of Unit Paediatric Surgery Hospital Raja Permaisuri Bainun, Ipoh
Hospital Raja Permaisuri Bainun, Ipoh
- Paediatric surgeon and Head of Paediatric Surgical Unit in Hospital Raja Permaisuri Bainun, Ipoh.
- Member of Specialty Education Sub-committee Paediatric Surgery.
- Assessor for Perioperative Mortality Review National and State Committee.
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Nuzhat Aziz
India
Nuzhat Aziz
Consultant Obstetrician and Gynaecologist
Fernandez Hospital, Hyderabad
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Pallavi Chandra
India
Pallavi Chandra
Consultant Obstetrician and Gynaecologist
Fernandez Hospital, Hyderabad
- Consultant Obstetrician and Gynaecologist in Fernandez Hospital, Hyderabad, India.
- Has conducted several workshops on electric fetal monitoring.
- An instructor in Advanced Life Support in Obstetrics Course.
- Main research, growth centiles, maternal near miss audit.
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Peter Reynolds
United Kingdom
Peter Reynolds
Consultant Neonatologist
St. Peter’s Hospital
Clinical Lead (Joint) South Wast Neonatal Network
Honorary Senior Lecturer
Royal Holloway University of London
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Rahmah Saaid
Malaysia
Rahmah Saaid
Consultant Obstetrician & Gynaecologist Department of Obstetrician & Gynaecologist
Universiti Malaya Medical Centre Kuala Lumpur
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Roziana Ariffin
Malaysia
Roziana Ariffin
Consultant Genetic Pathologist
Pantai Premier Pathology
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Sam Koh Chang Hoe
Singapore
Sam Koh Chang Hoe
Manager of Quality, Safety and Risk Management
KK Women’s and Children’s Hospital
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Samantha Chan I-Ling
Singapore
Samantha Chan I-Ling
Assistant Manager Quality, Safety and Risk Management (QSRM)
KK Women’s & Children’s Hospital
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Shireen Anne Nah
Malaysia
Shireen Anne Nah
Associate Professor Consultant Paediatric Surgeon & Head of Paediatric Surgery Unit Department of Surgery University of Malaya
UMMC
- Consultant Paediatric surgeon and Head of Paediatric Surgical Unit in UMMC.
- Completed 2 years research fellowship at UCL Institute of Child Health & Great Ormond Hospital for Children, London.
- Worked for 8 years in KK Women’s and Children’s Hospital, Singapore.
- Main interest in congenital colorectal conditions, health outcomes and quality of life.
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Sofiah Sulaiman
Malaysia
Sofiah Sulaiman
Consultant Obstetrician & Gynaecologist
Department of Obstetrician & Gynaecologist
Universiti Malaya Medical Centre Kuala Lumpur
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Sunil Jaiman
USA
Sunil Jaiman
Section Head, Placental Pathology Unit
Wayne State University School of Medicine Michigan
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Tan Lee Na
Malaysia
Tan Lee Na
Consultant Obstetrician & Gynaecologist
Maternal Fetal Medicine Specialist
Hospital Umum Sarawak
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Teck Yee Khong
Australia
Teck Yee Khong
Professor & Senior Consultant Pathologist
Women’s & Children’s Hospital North Adelaide
Professor & Senior Consultant Pathologist Women’s & Children’s Hospital North Adelaide, Australia
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Wong Chee Sing
Malaysia
Wong Chee Sing
Consultant Paediatrician & Neonatologist Department of Paediatrics
Hospital Raja Permaisuri Bainun Ipoh, Perak
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Wong Yin Ping
Malaysia
Wong Yin Ping
Associate Professor Department of Pathology
National University of Malaysia